Here's a preview of the Typekit UI we've been working on. After browsing around our library of fonts and making selections for your website, you open the Editor to configure everything. We've been trying to strike the right balance between application-style interaction and typographic clarity. I like how it's going.
We've been working on this with Jason Santa Maria who, as ever, has been a joy.
We'll be sending out our first invites soon. Sign up at the Typekit site to get on the list.