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Vol. 191, Issue 3 - toc1

A scanning electron micrograph of an infected mouse lung shows a Klebsiella pneumoniae bacterium (pink) snared in a neutrophil extracellular trap (green), a web of decondensed chromatin released by neutrophils to catch and kill pathogens. Papayannopoulos et al. reveal that neutrophil elastase degrades histones to promote chromatin decondensation and trap formation (image courtesy of Volker Brinkmann and Abdul Hakkim).


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Reference: Papayannopoulos et al. (2010) J. Cell Biol.191, 677-691.

Published on: November 1, 2010.

doi: 10.1083/jcb.201006052


Read the full article at: jcb.rupress.org/content/191/3/677.full

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Taken on November 1, 2010