Vol. 190, Issue 4 - toc1
An artistically rendered image showing the spatial separation of endocytic pathways in a migrating fibroblast. Clathrin-coated vesicles (blue) are nonpolarized, while clathrin-independent carriers (red) localize to the leading edge and caveolae (green) form at the rear of the cell. Howes et al. reveal that clathrin-independent internalization is the predominant endocytic pathway in fibroblasts.
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Reference: Howes et al. (2010) J. Cell Biol.190, 675-691.
Published on: August 23, 2010.
Read the full article at: jcb.rupress.org/content/190/4/675.full