Insomnia coffee shop & Skyline Chili @ High & 13th. Insomnia was open all night I believe, and had a patio out front that was always packed with scary/interesting people.
As I heard it, both Skyline and Insomnia were pushed out of this building by Campus Partners, who let on that it would be torn down and become some kind of office space or apartments. Instead, the building remained as-is and became a trendy Asian bar/restaurant.
Skyline moved a few blocks down the street, but was never successful and soon closed, leaving OSU's Cincinnatians without a place to get their hometown fix. Insomnia never resurfaced.