FAO Schwarz - 5th Avenue, New York, NY
This is the location in the movie "Big" where Tom Hanks and Robbert Loggia played "Heart and Soul" and "Chopsticks" on the giant piano (see note)
FAO Schwarz was also featured in another movie of the same year, "Big Business," starring Lily Tomlin and Bette Midler.
The giant clock greeted customers with "Welcome to our World of Toys" - I still have the cassette of that around here somewhere - my daughter wanted to listen to it over and over.... :)
See previous images in my set "Other Filming Locations" for a screenshot from the movie, Big