City Hall and bridges
Manhattan from 1 World Trade Center.
This is looking east, north east.
The bridge furthest north (left) is the Williamsburg Bridge that connects Manhattan with Queens (Long Island). The middle bridge is the Manhattan Bridge and the bridge furthest south (right) is the Brooklyn Bridge which connects Manhattan with Brooklyn, the first bridge to span the East River and one of the oldest, large suspension bridges in the United States. Walking across the Brooklyn Bridge is a great thing to do.
On the Manhattan side of the Brooklyn Bridge is City Hall and City Hall Park (to the right of the sign: Emigrant Industrial Savings Bank).
The large buildings closer to the river and bridge are city and federal courthouses and offices.
The right side of the frame is the northern tip of the financial district including Wall Street. My shot down there didn't work out because of sun on the window.
The other side of the river all the way to the horizon line is Long Island, right right side of the frame is northern Brooklyn, most of the frame is Queens.
The back/right of the horizon line is Kennedy Airport and beyond it the Atlantic Ocean.
There's plenty more detail visible here and over time I'll change this caption as we find things. Feel free to ID buildings in the comments.