PNNL researchers genetically engineered this microscopic marine diatom to become a biosensor for the sugar ribose. From left to right: The engineered diatom without fluorescence; the same diatom exhibiting blue fluorescence; and, when no ribose is present, the diatom generates a bright yellow fluorescence via fluorescence resonance energy transfer. Amnis Corp. of Seattle, Wash., used its ImageStream imaging flow cytometer to take these images.
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