Derek at His Thinnest (1991)
In early 1991, Alistair took this photo of me when I had lost a lot of weight -- it turned out that I had developed diabetes and my body was consuming itself because I couldn't process normal sugars and carbohydrates. Once I'd been in hospital for a week and started taking insulin, I plumped back up again.
Compare this to what I look like today (April 30, 2007), when I have also lost weight (though not nearly as much) because of my current chemotherapy and radiation treatment for colorectal cancer. There's also an explanatory blog post.
UPDATE: After I posted this picture, I ended up even thinner after my surgery in July 2007.
Man, those were some big glasses I had back in '91, though.