Che overlooking Plaza de la Revolucion_Cuba 035
During Che's time, this building was the Ministry of Industry (MININD). As the Minister of Industry, Che had an office on the top floor.
The Che memorial is based on the famous Alberto Korba picture.
Before this memorial was erected, another revolutionary slogan was displayed on the side of the building. It was possibly "Viva Cuba libre", but I can't remember since it has been nearly six years since I saw the photograph.