Broad Street and Erie Ave., Philadelphia
Now, thanks to rkthecasbah, we know that this is Broad Street and Erie Avenue.
Is this 30th Street Station? At first I thought it was, but now I'm not so sure. From Ben and Al's morgue files; probably from a commercial stock photography studio.
The partially-obscured billboard on the left is for "Golden Age Beer - the only beer brewed from Pure Springfield Water." from Fernwood Brewing Company. The Elite Drug Co. storefront can be seen, along with a subway entrance and signs for the Great Eastern Bus System and the Erie Barber Shop. I'm guessing this is from the 1940s.