Endocrine cells differentiated from human embryonic stem cells
Endocrine cells (insulin, blue; somatostatin, red; glucagon, green) develop in human islet-like
structures following transplantation of Pro-Islet™ into rodents. These cells produce insulin in response to glucose, effectively replacing the insulin that is lost in people with type 1 diabetes. ViaCyte has several CIRM grants to develop a stem cell-based therapy for type 1 diabetes based on this work.
Image taken by Kuniko Kadoya, PhD at Viacyte, Inc.