July 30, 2013 - Question 3
3) A 5-year-old African American male presents with weight loss, fevers, and a painless swelling in the area of his jaw. The patient has no significant past medical history, and was adopted as an infant. CBC reveals anemia and lymphocytosis. Biopsy findings are seen in image below. Which of the following is true of this patient’s condition?
a. A bcl-2 mutation may be present
b. Cells are generally CD5+
c. The most common genetic rearrangement is t(14;18) (q24;q32)
d. C-myc gene translocation is unique to this patient’s condition
e. The endemic form of this patient’s condition is associated with Epstein-Barr virus positivity.
Check answer here.
Source: BoardVitals, 7/30/2013