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June 18, 2013 - Question 1 | by Pathology Outlines
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June 18, 2013 - Question 1

1) A 64-year old African American male with history of hypertension and COPD presents for evaluation of an itchy skin rash of several years’ duration. He has been evaluated for this rash several times, and has previously had many inconclusive biopsies. He has failed treatment with multiple courses of steroids as well as other topical medications. On physical examination, there are multiple patches and, plaques, as well as generalized erythroderma located in the bathing trunk distribution. The patient undergoes biopsy of one of the skin lesions, which can be seen below. Which of the following immunophenotypes is most consistent with this diagnosis?

 

a. CD2+, CD3+, CD5+, and CD7-

b. CD2-, CD3-, CD5 -, and CD7-

c. CD2+, CD3+, CD5-, and CD7+

d. CD2-, CD3+, CD5+, and CD7+

e. CD2+, CD3-, CD5+, and CD7+

 

Check answer here.

 

Source: BoardVitals, 6/18/2013

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Uploaded on June 18, 2013