Mucoepidermoid carcinoma, low grade - Case 199

Mucoepidermoid carcinoma is a rare lung tumor tht usually arises within the central bronchi. Typical cases contain mucus-secreting goblet cells, intermediate cells and squamous cells. Low grade tumors predominate and are characterized by mucous-filled cystic structures without significant cytologic atypia. High grade tumors tend to have solid areas of growth with significant cytologic atypia and mitotic activity. HIgh grade mucoepidermoid carcinomas may contain a low grade component.

 

This image shows small mucinous cysts within sheets of large cells without cytologic atypia. The stroma is heavily infiltrated by chronic inflammatory cells.

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