Clever Wall mural in Yellow Springs, Ohio. In my original comment, I said " I wish I knew the story." Over a year later, someone with local knowledge posted this comment:
"Here is the REAL story... This mural was commissioned by Les Gilford and was painted by Jennifer Veutling and her sister. Les and the crew on this mural renovated the building from Joe Holly's Dry cleaners (in existance for about 50 years) into " Would You, Could You" In a Frame, a contemporary art gallery. they worked long and hard on this renovation and were very proud of their accomplishments, hence the mural. From left to right Scooby, Junior (Chris), Teaspoon (now deceased) and Les Gilford. "
Now I'm glad to know "the rest of the story" thanks to InaFrame1!