Vietnamese named : Thủy Tiên hoa trắng
Common names : Daffodil, Chinese Sacred Lily, Bunch-flowered Narcissus, Joss flower
Scientist name : Narcissus tazetta L
Family : Amaryllidaceae. Họ Hoa Huệ đỏ.
Biochem Cell Biol. 2002;80(2):271-7.
Gene expression of immunomodulatory cytokines induced by Narcissus tazetta lectin in the mouse.
Ooi LS, Liu F, Ooi VE, Ng TB, Fung MC.
Department of Biology, The Chinese University of Hong Kong, Shatin.
The immunomodulation of Narcissus tazetta lectin (NTL) on the induction of gene expression of cytokines in the mouse was studied using specific cytokine primers, total RNA isolated from mouse splenocytes and macrophages, and reverse transcription-polymerase chain reaction (RT-PCR). For comparison, a fungal antimitogenic lectin from Agaricus bisporus (ABL) was used to test and compare the acute (kinetic) induction of cytokine gene expression. NTL was able to induce the expression of IL-1beta, TNF-alpha, and immunoreactive nitric oxide synthase (NOS) in both splenocytes and macrophages in vivo after 10-day consecutive peritoneal injections of 5 mg NTL x kg(-1) x day(-1) in the mouse. Nevertheless, the expression levels of IFN-gamma and TGF-beta were markedly increased in macrophages, and the levels of IL-2 and IL-4 were up-regulated only in splenocytes. From the kinetic pattern of cytokine induction and gene expression, ABL appeared to induce the up-regulation of IL-1beta and TNF-alpha in splenocytes up to 24 h, whereas NTL showed a more sustained effect on the expression of these cytokines in macrophages. While NTL manifested TGF-beta expression at the onset of 12 and 24 h in macrophages and splenocytes, respectively, ABL induced TGF-beta in neither splenocytes nor macrophages. After injection of NTL, stem-cell factor was clearly down-regulated in macrophages at 24 and 48 h but up-regulated in splenocytes at the end of 24 h. The immunopotentiating effect of NTL is quite similar to that of LZ-8, a fungal immunomodulatory lectin isolated from the Chinese premier medicinal mushroom Ganoderma lucidium. However, the mechanism of immunomodulation of NTL still awaits to be elucidated.
Narcissus tazetta L.
Narcissus tazetta L. subsp. aureus (Loisel.) Baker
Narcissus tazetta L. subsp. italicus (Ker. Gawl.) Baker
Narcissus tazetta L. subsp. tazetta
bunchflower daffodil, bunchflower narcissi, bunch-flowered narcissus, Chinese sacred lily, cream narcissus, daffodil, French daffodil, jonquil, narcissus, polyanthus narcissus, tazetta, tazetta daffodil.
Amaryllidaceae (New South Wales and Western Australia)
Liliaceae (Victoria, Tasmania and South Australia)
The exact native range of this species is obscure. It is thought to be native to northern Africa (i.e. Algeria, Egypt, Libya and Morocco), southern Europe (i.e. France, Portugal, Spain, Albania, Greece, Italy and Yugoslavia), western Asia (i.e. Cyprus, Iran, Iraq, Israel, Jordan, Lebanon, Syria and Turkey) and southern Russia.
Naturalised in many parts of southern Australia (i.e. in south-western Western Australia, in the southern parts of South Australia, in Victoria and in some parts of eastern New South Wales).
Also naturalised on Lord Howe Island and in many other temperate regions of the world (e.g. in the USA, China and Japan).
Jonquil (Narcissus tazetta) is regarded as an environmental weed in Victoria, South Australia and Western Australia.