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It is one of the best preserved and most beautiful structures on Curetes Street. It was built before 138 A.D by P.Quintilius and was dedicated to the Emperor Hadrian, who came to visit the city from Athens in 128 A.D The facade of the temple has four Corinthian columns supporting a curved arch, in the middle of which contains a relief of Tyche, goddess of victory. The side columns are square. The pedestal with inscriptions in front of the temple, are the bases for the statues of the emperors between 293-305 CE, Diocletian, Maximian, Constantius I, and Galerius; the originals of the statues have not been found yet.

The House of the Virgin (Meryemana in Turkish), located in a nature park between Ephesus and Seljuk, is believed to be the last residence of the Virgin Mary, mother of Jesus. The peaceful site is sacred to both Christians and Muslims, and is visited by many tourists and pilgrims.

Proceed to the Medical Center of the ancient world, Asklepion where the first psychological treatment had been used and which was dedicated to the God of Health, Asklepios.