My calico cat "Cookie" eyes a goldfish. No animal was harmed and no "Photoshop" was used in the making of this photograph. (It was used to touch-up small bits of flotsam & jetsam, but not used in the making of...)
This is a single shot with minimal Photoshopping to clean up the bubbles and small bits of fish-poop in the water. Hassleblad medium format camera; 250mm telephoto with extension tube @ f/45 and strobe lighting; FUJI Velvia 50, scanned with Nikon Coolscan 9000 at full resolution. Shot was a personal experiment, and entered into competition in our local camera club.
Got 2nd place.