I lived in this neighborhood (Federal Hill) for 17 years. I worked on the 25th floor of the tallest building on the left for 5 years. It was then the USF&G Insurance Company. I could see the Chesapeake Bay Bridge from my desk, My great grandfather's company, Egerton Brothers, was on the same site for many years.
The tall building on the right is the World Trade Center.
The Streets of Baltimore by Bobby Bare on YouTube (Thanks Johan!)