Side by Side
This is a comparison of the new Canon Powershot S5 IS and the Canon Powershot S2 IS.
You can see the buttons have moved. I always had the customizable button programed for ISO anyway so that actually ended up in the same position on the camera, but since it is now the second button instead of the third I keep missing it. And the new placement of the customizable button makes it pretty useless. When the LCD panel is open it is difficult to reach with your left hand. And with it closed it is not much better, that just isn't a place I ever have my hand near. When I use the camera with both hands, my left goes underneath to support the camera.