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Dante Inferno's photostream |
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My Great-Grandfather
HCN2-MET-272-cGMP
Note that MET-272 keeps the same hydrophobic interaction between the two ligands, at the same diffrence.
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Uploaded on Oct 5, 2011
HCN2-cAMP-Met272
Note that MET-272 keeps the same hydrophobic interaction between the two ligands, at the same diffrence.
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Uploaded on Oct 5, 2011
HCN2-cGMP-Boung-All3Fit
This shows that all 3 ligands fit into the cGMP bound form (I turned the spheres off for the image as it was hard to see)
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Uploaded on Oct 5, 2011
HCN2-Met252-synAnti-cAMP
My second choice would be MET-252. It shows a very obvious reaction to cAMP vs cGMP.
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Uploaded on Oct 5, 2011
ILE-636-Clash-HCN2
syn-cAMP with HCN2
Now I turned on the spheres and you can clearly see that it is a gigantic steric clash
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Uploaded on Oct 5, 2011
HCN2-synAniComp
I overlayed syn-cAMP onto HCN2 with anti-cAMP. Even without switching to spheres you can see the obvious steric clash.
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Uploaded on Oct 5, 2011
HCN2 ChangesOnRightSide
I initially thought this large change on the right side of the pocket between cGMP and cAMP...
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Uploaded on Oct 5, 2011
My new glasses
I have new glasses and like how I look for once. Well, except the hair.
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Uploaded on Aug 17, 2011
My new glasses
I have new glasses and like how I look for once. Well, except the hair.
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Uploaded on Aug 17, 2011
My whiteboard at work
My whiteboard at work. Mostly, but not all my writing.
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Uploaded on Jul 29, 2011
pointSources
A set of radioactive point sources from my lab. Fuluny's fault that 133Ba is upside down.
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Uploaded on Jul 26, 2011
The OTHER labs whiteboard
This is what the *OTHER* labs whiteboard looks like. Even crazier then ours, and obviously used less.
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Uploaded on Jul 24, 2011
The OTHER labs whiteboard
This is what the *OTHER* labs whiteboard looks like. Even crazier then ours, and obviously used less.
Some rights reserved
Uploaded on Jul 24, 2011
